A one-year prospective comparison of calcium supplementation, low dose continuous, and moderate dose cyclical oestrogen and progestagen replacement therapy in the protection of bone mass

After 6 months of calcium supplementation, 86 recently postmenopausal women chose either to remain on calcium or to add hormone replacement therapy. Women who chose hormones were allocated at random to either a low dose continuous (conjugated oestrogens, 0-3 mg/ day and medroxyprogesterone, 2-5 mg/day) or a moderate dose cyclical (conjugated oestrogens, 0-625 mg/ day, and medroxyprogesterone, 5 mg/day) regimen. Lumbar spine bone mineral density …