Chronic venous insufficiency and leg ulceration: Principles and vascular biology

DEFINITIONS Chronic Venous Insufficiency Chronic venous insufficiency (CVI) is a term that is used to describe changes in the leg that include a variety of different clinical problems, which are caused by several types of abnormalities in the veins, and which may occur at a number of different locations in the leg. For these reasons it has been difficult to make accurate comparisons of reports of chronic venous insufficiency from different …