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Investigation of human platelet alloantigens and...
Journal article

Investigation of human platelet alloantigens and glycoproteins using non-radioactive immunoprecipitation

Abstract

Sensitive techniques to detect platelet antibodies are needed for the investigation of immune thrombocytopenic syndromes such as neonatal alloimmune thrombocytopenia and post-transfusion purpura. Radioimmunoprecipitation has proved useful in the investigation of platelet-antibody interactions; however, the requirement for a radioactive label is a disadvantage. We describe the immunoprecipitation of human platelet proteins labelled with …

Authors

Smith JW; Hayward CPM; Warkentin TE; Horsewood P; Kelton JG

Journal

Journal of Immunological Methods, Vol. 158, No. 1, pp. 77–85

Publisher

Elsevier

Publication Date

January 1993

DOI

10.1016/0022-1759(93)90260-e

ISSN

0022-1759