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Genetic Loci Associated with Platelet Traits and...
Journal article

Genetic Loci Associated with Platelet Traits and Platelet Disorders

Abstract

Genetic investigations have led to important advances in our knowledge of genes, proteins, and microRNA that influence circulating platelet counts, platelet size, and function. The application of genome-wide association studies (GWAS) to platelet traits has identified multiple loci with a significant association to platelet number, size, and function in aggregation and granule secretion assays. Moreover, the genes altered by disease-causing …

Authors

Bunimov N; Fuller N; Hayward C

Journal

Seminars in Thrombosis and Hemostasis, Vol. 39, No. 03, pp. 291–305

Publisher

Thieme

Publication Date

April 2013

DOI

10.1055/s-0033-1334466

ISSN

0094-6176