Journal article
Palmitoyl‐dl‐Carnitine is a Multitarget Inhibitor of Pseudomonas aeruginosa Biofilm Development
Abstract
Bacteria growing in biofilms are often in metabolic and physiological states that do not respond well to antibiotics, and thus, are major contributors to chronic diseases. Biofilm inhibitors, therefore, have the potential to be used alone or as adjuvants to conventional antibiotic therapies. Here, we screened a chemically diverse collection of protein kinase inhibitors for molecules that perturb biofilm development. Among the inhibitory …
Authors
Wenderska IB; Chong M; McNulty J; Wright GD; Burrows LL
Journal
ChemBioChem, Vol. 12, No. 18, pp. 2759–2766
Publisher
Wiley
Publication Date
December 16, 2011
DOI
10.1002/cbic.201100500
ISSN
1439-4227