Journal article
Genetic and lifestyle risk factors for MRI-defined brain infarcts in a population-based setting
Abstract
OBJECTIVE: To explore genetic and lifestyle risk factors of MRI-defined brain infarcts (BI) in large population-based cohorts.
METHODS: We performed meta-analyses of genome-wide association studies (GWAS) and examined associations of vascular risk factors and their genetic risk scores (GRS) with MRI-defined BI and a subset of BI, namely, small subcortical BI (SSBI), in 18 population-based cohorts (n = 20,949) from 5 ethnicities (3,726 with BI, …
Authors
Chauhan G; Adams HHH; Satizabal CL; Bis JC; Teumer A; Sargurupremraj M; Hofer E; Trompet S; Hilal S; Smith AV
Journal
Neurology, Vol. 92, No. 5,
Publisher
Wolters Kluwer
Publication Date
January 29, 2019
DOI
10.1212/wnl.0000000000006851
ISSN
0028-3878