Journal article
The heterochromatic chromosome caps in great apes impact telomere metabolism
Abstract
In contrast with the limited sequence divergence accumulated after separation of higher primate lineages, marked cytogenetic variation has been associated with the genome evolution in these species. Studying the impact of such structural variations on defined molecular processes can provide valuable insights on how genome structural organization contributes to organismal evolution. Here, we show that telomeres on chromosome arms carrying …
Authors
Novo C; Arnoult N; Bordes W-Y; Castro-Vega L; Gibaud A; Dutrillaux B; Bacchetti S; Londoño-Vallejo A
Journal
Nucleic Acids Research, Vol. 41, No. 9, pp. 4792–4801
Publisher
Oxford University Press (OUP)
Publication Date
May 1, 2013
DOI
10.1093/nar/gkt169
ISSN
0305-1048