Journal article
Determination of malondialdehyde in human plasma by fully automated solid phase analytical derivatization
Abstract
Analytical derivatization (AD) increases the sensitivity of analysis by one to three orders of magnitude, stabilizes labile analytes and converts them into readily extractable products. Using a variant of this technique, we applied solid phase analytical derivatization (SPAD) to fully automate extraction, derivatization and liquid chromatography. The resulting device (AutoSPAD) determined malonyldialdehyde (MDA) from biological fluids. This …
Authors
Lord HL; Rosenfeld J; Volovich V; Kumbhare D; Parkinson B
Journal
Journal of Chromatography B, Vol. 877, No. 13, pp. 1292–1298
Publisher
Elsevier
Publication Date
May 1, 2009
DOI
10.1016/j.jchromb.2008.12.035
ISSN
1570-0232