Journal article
Determination of sulphinpyrazone in patient plasma by gas chromatography
Abstract
Two variations of a method for the determination of sulphinpyrazone in plasma by gas chromatography and by gas chromatography/mass spectrometry are described. Both are based upon methylation of sulphinpyrazone by phase transfer catalysis with methyl iodide as the alkylating agent. The range of plasma concentrations in patients with transient cerebral ischemia being treated with sulphinpyrazone as well as hemodialysis patients being treated for …
Authors
Rosenfeld J; Buchanan M; Powers P; Hirsh J; Barnett HJM; Stuart RK
Journal
Thrombosis Research, Vol. 12, No. 2, pp. 247–255
Publisher
Elsevier
Publication Date
2 1978
DOI
10.1016/0049-3848(78)90296-7
ISSN
0049-3848