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Determination of sulphinpyrazone in patient plasma...
Journal article

Determination of sulphinpyrazone in patient plasma by gas chromatography

Abstract

Two variations of a method for the determination of sulphinpyrazone in plasma by gas chromatography and by gas chromatography/mass spectrometry are described. Both are based upon methylation of sulphinpyrazone by phase transfer catalysis with methyl iodide as the alkylating agent. The range of plasma concentrations in patients with transient cerebral ischemia being treated with sulphinpyrazone as well as hemodialysis patients being treated for …

Authors

Rosenfeld J; Buchanan M; Powers P; Hirsh J; Barnett HJM; Stuart RK

Journal

Thrombosis Research, Vol. 12, No. 2, pp. 247–255

Publisher

Elsevier

Publication Date

February 1978

DOI

10.1016/0049-3848(78)90296-7

ISSN

0049-3848