Journal article
A retrospective analysis of the relationship between changes in serum PSA, palliative response and survival following systemic treatment in a Canadian randomized trial for symptomatic hormone-refractory prostate cancer
Abstract
BACKGROUND: To investigate the relationship between changes in serum PSA, palliative response and survival following systemic treatment for symptomatic hormone-refractory prostate cancer (HRPC).
PATIENTS AND METHODS: A retrospective review of 161 patients, treated with mitoxantrone and prednisone (M + P) (n = 80), or prednisone alone (P) (n = 81) from a Canadian randomized phase III clinical trial. PSA response was defined by > or =50% decline …
Authors
Dowling AJ; Panzarella T; Ernst DS; Neville AJ; Moore MJ; Tannock IF
Journal
Annals of Oncology, Vol. 12, No. 6, pp. 773–778
Publisher
Elsevier
Publication Date
June 2001
DOI
10.1023/a:1011116626590
ISSN
0923-7534