Gene therapy for lung injury

This chapter discusses gene therapy and its use in mitigating pulmonary pathology involving acute or chronic lung injury. Strategies of gene transfer can be directed at genomic integrated long-term (permanent) expression, long-term nonintegrated expression, or short-term nonintegrated expres- sion. Gene therapy is unique among clinical interventions in that it has the potential to generate a prolonged effect at the cellular level that is not …