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Spontaneous appearance of uterine tumors in...
Journal article

Spontaneous appearance of uterine tumors in vehicle and 3-methylcholanthrene-treated Wistar rats

Abstract

During the conduct of a study designed to determine the effect of 3-methylcholanthrene (3-MC), a synthetic polycyclic aromatic hydrocarbon (PAH) that acts through the aryl hydrocarbon receptor (AhR), on uterine contractility in Wistar rats, uterine tumors were identified in both vehicle and 3-MC-treated animals. The objective of the current study was to describe the histological characteristics of these tumors. Sexually mature female rats (110 …

Authors

Anger DL; Crankshaw DJ; Foster WG

Journal

Reproductive Toxicology, Vol. 22, No. 4, pp. 760–764

Publisher

Elsevier

Publication Date

11 2006

DOI

10.1016/j.reprotox.2006.07.007

ISSN

0890-6238