Journal article
HFSA guidelines for the management of patients with heart failure due to left ventricular systolic dysfunction - Pharmacological approaches
Abstract
Background. The renin-angiotensin system plays an important part in the pathogenesis of congestive heart failure (CHF). This study evaluated the effect of an angiotensin II type I receptor antagonist on exercise tolerance and symptoms of CHF. Methods and Results. In this multicenter, double-blind, parallel-group study, 844 patients with CHF were randomized to 12 weeks treatment with placebo (n=211) or candesartan cilexetil 4 mg (n=208), 8 mg …
Authors
Adams J; Baughman KL; Dec WG; Elkayam U; Forker AD; Gheorghiade M; Hermann D; Konstam MA; Liu P; Massie BM
Journal
Congestive Heart Failure, Vol. 6, No. 1, pp. 11–40
Publication Date
December 1, 2000
ISSN
1079-7998