Journal article
The Effects of Extracellular Calcium-Sensing Receptor Ligands on the Contractility of Pregnant Human Myometrium In Vitro
Abstract
Ligands for extracellular calcium-sensing (CaS) receptors inhibit oxytocin-induced contractions of the rat’s uterus. In this study, we investigated whether the CaS receptor ligands calindol, cinacalcet, and calhex 231 have similar effects on pregnant human myometrium. We compared their effects to those of the calcium-channel blocker nifedipine. In conventional concentration–effect experiments, both the mean contractile force (MCF) and the …
Authors
Crankshaw DJ; Pistilli MJ; O’Brien YM; Sweeney EM; Dockery P; Holloway AC; Morrison JJ
Journal
Reproductive Sciences, Vol. 20, No. 8, pp. 882–890
Publisher
Springer Nature
Publication Date
8 2013
DOI
10.1177/1933719112468949
ISSN
1933-7191