Journal article
The challenges of measuring bleeding outcomes in clinical trials of platelet transfusions
Abstract
BACKGROUND: Many platelet (PLT) transfusion trials now use bleeding as a primary outcome; however, previous studies have shown a wide variation in the amount (5%-70%) and type of bleeding documented. Differences in the way bleeding has been identified, recorded, and graded may account for some of this variability. This study's aim was to compare trials' method to document and grade bleeding.
STUDY DESIGN AND METHODS: Data were collected via …
Authors
Estcourt LJ; Heddle N; Kaufman R; McCullough J; Murphy MF; Slichter S; Wood EM; Stanworth SJ; Collaborative BEFST
Journal
Transfusion, Vol. 53, No. 7, pp. 1531–1543
Publisher
Wiley
Publication Date
July 2013
DOI
10.1111/trf.12058
ISSN
0041-1132