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The application of latent class analysis for...
Journal article

The application of latent class analysis for diagnostic test validation of chronic Trypanosoma cruzi infection in blood donors

Abstract

The main strategy to prevent transfusion-associated Chagas disease is the identification of T. cruzi-infected blood donors by serological screening tests, however there is no perfect serological gold standard. We evaluated an enzyme immunoassay (EIA), an indirect hemaglutination (IHA), and an indirect immunofluorescence (IIF) test for detecting T. cruzi antibodies in Brazilian blood donors. The results were submitted to latent class analysis, …

Authors

Langhi DM; Bordin JO; Castelo A; Walter SD; Moraes-Souza H; Stumpf RJ

Journal

The Brazilian Journal of Infectious Diseases, Vol. 6, No. 4, pp. 181–187

Publisher

FapUNIFESP (SciELO)

Publication Date

8 2002

DOI

10.1590/s1413-86702002000400005

ISSN

1413-8670