Nicotine

Nicotine (54-11-5) is a highly toxic alkaloid found in tobacco plants and tobacco products. It is also used as a smoking cessation pharmacotherapy. Nicotine is an agonist of nicotinic acetylcholine receptors that are found in the central and autonomic nervous systems as well as many peripheral tissues. Both acute and chronic exposure to nicotine is associated with adverse effects on multiple organ systems including the nervous, respiratory, and cardiovascular systems.