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Intestinal scavenger receptor class B type I as a...
Journal article

Intestinal scavenger receptor class B type I as a novel regulator of chylomicron production in healthy and diet-induced obese states

Abstract

The small intestine contributes to diabetic dyslipidemia through the overproduction of apolipoprotein B48 (apoB48)-containing chylomicron particles. An important regulator of chylomicron generation is dietary lipid absorption, underlining the potential involvement of intestinal lipid transporters for developing dyslipidemia. Intestinal expression of scavenger receptor class B type I (SR-BI) has been found to be upregulated in animal models of …

Authors

Lino M; Farr S; Baker C; Fuller M; Trigatti B; Adeli K

Journal

AJP Gastrointestinal and Liver Physiology, Vol. 309, No. 5, pp. g350–g359

Publisher

American Physiological Society

Publication Date

September 1, 2015

DOI

10.1152/ajpgi.00086.2015

ISSN

0193-1857