Journal article
cAMP-independent control of twitching motility in Pseudomonas aeruginosa
Abstract
ABSTRACT FimV is a Pseudomonas aeruginosa inner membrane hub protein that modulates levels of the second messenger, cyclic AMP (cAMP), through activation of the adenylate cyclase, CyaB. Although type IVa pilus (T4aP)-dependent twitching motility is modulated by cAMP levels, mutants lacking FimV are twitching impaired, even when exogenous cAMP is provided. Here we further define FimV’s cAMP-dependent and -independent regulation of twitching. We …
Authors
Buensuceso RNC; Daniel-Ivad M; Kilmury SLN; Harvey H; Howell PL; Burrows LL
Journal
, , ,
Publisher
Cold Spring Harbor Laboratory
DOI
10.1101/116954
ISSN
2692-8205