Journal article
Differences in Brain Glucose Metabolism Between Responders to CBT and Venlafaxine in a 16-Week Randomized Controlled Trial
Abstract
OBJECTIVE: Neuroimaging investigations reveal changes in glucose metabolism (fluorine-18-fluorodeoxyglucose positron emission tomography [PET]) associated with response to disparate antidepressant treatment modalities, including cognitive behavior therapy (CBT), antidepressant pharmacotherapies, and deep brain stimulation. Using a nonrandomized design, the authors previously compared changes following CBT or paroxetine in depressed patients. In …
Authors
Kennedy SH; Konarski JZ; Segal ZV; Lau MA; Bieling PJ; McIntyre RS; Mayberg HS
Journal
American Journal of Psychiatry, Vol. 164, No. 5, pp. 778–788
Publisher
American Psychiatric Association Publishing
Publication Date
May 2007
DOI
10.1176/ajp.2007.164.5.778
ISSN
0002-953X
Associated Experts
Fields of Research (FoR)
Medical Subject Headings (MeSH)
AdultBrainCerebral CortexCognitive Behavioral TherapyCombined Modality TherapyCyclohexanolsDepressive Disorder, MajorFemaleFluorodeoxyglucose F18Functional LateralityGlucoseHumansLimbic SystemMaleMiddle AgedPositron-Emission TomographySelective Serotonin Reuptake InhibitorsTreatment OutcomeVenlafaxine Hydrochloride