Patterning an Epidermal Field:DrosophilaLozenge, a Member of the AML-1/Runt Family of Transcription Factors, Specifies Olfactory Sense Organ Type in a Dose-Dependent Manner

Sense organ development in the Drosophila antenna is initiated by the selection of a founder cell from an epidermal field. This cell is believed to recruit neighbours to form a cluster of cells which then divides to form a mature sense organ. In most systems so far studied, sense organ type appears to be specified by the identity of proneural genes involved in the selection of precursors. The regulation of proneural gene expression is, in turn, …