3D printing of gels with integrated vascular channels for cell culture using a microfluidic printhead

This work details the development of a three dimensional (3D) printing system with a modified microfluidic print-head used for the generation of complex vascular tissue scaffolds. The print-head features an integrated coaxial nozzle that allows the fabrication of hollow, calcium-polymerized alginate tubes that can be easily patterned using 3D-bioprinting techniques. This microfluidic design allows the incorporation of a wide range of scaffold …