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Peptide modified gold coated polyurethanes for...
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Peptide modified gold coated polyurethanes for thrombin inhibition

Abstract

The effects of peptide modified gold coated polyurethanes on thrombin adsorption and thrombin inhibition were examined. The polyurethanes were chemisorbed with a thiol containing thrombin inhibiting peptide. Thrombin adsorption to the polyurethane films was measured from plasma at different dilutions and from phosphate buffered saline. The biotinylated thrombin on the surface was detected by binding to alkaline phosphatase conjugated …

Authors

Sheardown H; Brash JL

Volume

1

Publication Date

December 1, 1996

Conference proceedings

Transactions of the Annual Meeting of the Society for Biomaterials in Conjunction with the International Biomaterials Symposium