Journal article
5-HT2A and 5-HT3 receptors contribute to the exacerbation of targeted and non-targeted effects of ionizing radiation-induced cell death in human colon carcinoma cells
Abstract
Purpose: Serotonin (5-HT) is implicated in the underlying mechanisms which mediate cell death following ionizing radiation exposure, however, effects appear to be cell type-dependent. We sought to further characterize the role of 5-HT and 5-HT receptors (5-HTRs) in the exacerbation of cell death following ionizing radiation exposure in human colon carcinoma cells.Materials and methods: We examined the clonogenic survival of colon carcinoma …
Authors
Curtis JJ; Vo NTK; Seymour CB; Mothersill CE
Journal
International Journal of Radiation Biology, Vol. 96, No. 4, pp. 482–490
Publisher
Taylor & Francis
Publication Date
April 2, 2020
DOI
10.1080/09553002.2020.1704911
ISSN
0955-3002