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Clinical pre‐test probability adjusted versus...
Journal article

Clinical pre‐test probability adjusted versus age‐adjusted D‐dimer interpretation strategy for DVT diagnosis: A diagnostic individual patient data meta‐analysis

Abstract

BACKGROUND: To increase the clinical usefulness of the D-dimer test in diagnosis of deep vein thrombosis (DVT), two strategies have been proposed: the age-adjusted, and the clinical pre-test probability (CPTP) adjusted interpretation. However, it is not known which of these strategies is superior. OBJECTIVE: To conduct an individual patient data (IPD) meta-analysis that compares the sensitivity, specificity, negative predictive value (NPV), and …

Authors

Parpia S; Takach Lapner S; Schutgens R; Elf J; Geersing G-J; Kearon C

Journal

Journal of Thrombosis and Haemostasis, Vol. 18, No. 3, pp. 669–675

Publisher

Elsevier

Publication Date

March 2020

DOI

10.1111/jth.14718

ISSN

1538-7933