Journal article
A study of nitric oxide dynamics in a growing biofilm using a density dependent reaction-diffusion model
Abstract
One of a number of critical roles played by NO· as a chemical weapon (generated by the immune system) is to neutralize pathogens. However, the virulence of pathogens depends on the production activity of reductants to detoxify NO·. Broad reactivity of NO· makes it complicated to predict the fate of NO· inside bacteria and its effects on the treatment of any infection. Here, we present a mathematical model of biofilm response to NO·, as a …
Authors
Ghasemi M; Jenkins B; Doxey AC; Sivaloganathan S
Journal
Journal of Theoretical Biology, Vol. 485, ,
Publisher
Elsevier
Publication Date
January 2020
DOI
10.1016/j.jtbi.2019.110053
ISSN
0022-5193