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Starving the Gut: A Deficit of Butyrate in the...
Journal article

Starving the Gut: A Deficit of Butyrate in the Intestinal Ecosystem of Children With Intestinal Failure

Abstract

BACKGROUND: Intestinal epithelial integrity is influenced by short-chain fatty acids (SCFAs) and is of critical importance for children with intestinal failure (IF) given the known devastating infectious and gastrointestinal complications. The composition of the microbiome in IF represents an important variable in the physiology and prognosis of this disease. AIM: We sought to compare the intestinal microbiome and SCFA concentration of children …

Authors

Dowhaniuk JK; Szamosi J; Chorlton S; Owens J; Mileski H; Clause R; Pernica JM; Bowdish DME; Surette MG; Ratcliffe EM

Journal

Journal of Parenteral and Enteral Nutrition, Vol. 44, No. 6, pp. 1112–1123

Publisher

Wiley

Publication Date

August 2020

DOI

10.1002/jpen.1715

ISSN

0148-6071