Journal article
Randomized window of opportunity trial evaluating high-dose vitamin D in breast cancer patients
Abstract
PurposeEpidemiologic and preclinical data suggest a potential role for vitamin D in breast cancer treatment and prevention. However, results of prospective randomized trials are inconsistent. The objective of this study was to assess the effects of high-dose cholecalciferol (vitamin D3) on breast tumour proliferation and apoptosis.MethodsWe conducted a prospective, randomized, phase 2, double-blinded pre-surgical window of opportunity trial. …
Authors
Arnaout A; Robertson S; Pond GR; Vieth R; Jeong A; Hilton J; Ramsey T; Clemons M
Journal
Breast Cancer Research and Treatment, Vol. 178, No. 2, pp. 347–356
Publisher
Springer Nature
Publication Date
November 2019
DOI
10.1007/s10549-019-05392-9
ISSN
0167-6806