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Journal article

Quantifying Antibody Responses Induced by Antigen-Agnostic Immunotherapies

Abstract

As the development and clinical application of cancer immunotherapies continue to expand, so does the need for novel methods to dissect their mechanisms of action. Antibodies are important effector molecules in cancer therapies due to their potential to bind directly to surface-expressed antigens and facilitate Fc receptor-mediated uptake of antigens by antigen-presenting cells. Quantifying antibodies that are specific for defined antigens is …

Authors

van Vloten JP; Klafuric EM; Karimi K; McFadden G; Petrik JJ; Wootton SK; Bridle BW

Journal

Molecular Therapy — Methods & Clinical Development, Vol. 14, , pp. 189–196

Publisher

Elsevier

Publication Date

September 2019

DOI

10.1016/j.omtm.2019.06.010

ISSN

2399-6951