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New Advances in Amino Acid Profiling in Biological...
Journal article

New Advances in Amino Acid Profiling in Biological Samples by Capillary Electrophoresis-Mass Spectrometry

Abstract

Capillary electrophoresis-mass spectrometry (CE-MS) offers a high efficiency microseparation platform for amino acid profiling when analyzing volume-restricted biological samples, such as a dried blood spot punch. Direct analysis of amino acids and their analogs is routinely achieved using strongly acidic buffer conditions under positive-ion mode detection with a coaxial sheath liquid interface for electrospray ionization (ESI). New advances in …

Authors

Shanmuganathan M; Britz-McKibbin P

Journal

Methods in Molecular Biology, Vol. 2030, , pp. 327–350

Publisher

Springer Nature

Publication Date

2019

DOI

10.1007/978-1-4939-9639-1_25

ISSN

1064-3745