Journal article
Secretion of recombinant proteins from hydroxyethyl methacrylate‐methyl methacrylate capsules
Abstract
Current human gene therapy relies on genetic modification of the patient's own cells. An alternate nonautologous approach is to use universal cell lines engineered to secrete therapeutic products. Protection with immunoisolation devices before implantation would allow the use of the same recombinant cell line for treating different patients, thus potentially lowering the cost of treatment. To study the properties of a mechanically stable …
Authors
Tse M; Uludag H; Sefton MV; Chang PL
Journal
Biotechnology and Bioengineering, Vol. 51, No. 3, pp. 271–280
Publisher
Wiley
Publication Date
August 5, 1996
DOI
10.1002/(sici)1097-0290(19960805)51:3<271::aid-bit3>3.0.co;2-a
ISSN
0006-3592