Journal article
Restraint stress induced gut dysmotility is diminished by a milk oligosaccharide (2′-fucosyllactose) in vitro
Abstract
BACKGROUND: Stress causes severe dysmotility in the mammalian gut. Almost all research done to date has concentrated on prevention of stress-induced altered gut motility but not on treatment. We had previously shown that intraluminal 2'FL could acutely moderate propulsive motility in isolated mouse colonic segments. Because 2'FL appeared to modulate enteric nervous system dependent motility, we wondered if the oligosaccharide could reverse the …
Authors
Farhin S; Wong A; Delungahawatta T; Amin JY; Bienenstock J; Buck R; Kunze WA
Journal
PLOS ONE, Vol. 14, No. 4,
Publisher
Public Library of Science (PLoS)
DOI
10.1371/journal.pone.0215151
ISSN
1932-6203