Journal article
Potential Application of a New Screening Test for α-Thalassemia-1 Carriers
Abstract
A murine hybridoma cell line secreting monoclonal anti-human embryonic zeta-globin chain antibody has been established. Using this monoclonal antibody, a slot blot immunobinding assay for the detection of zeta-globin chains in adult hemolysates has been developed. This simple test can identify individuals who are alpha-thalassemia-1 carriers due to the (-SEA/) deletion. It is proposed that this test should be made generally available in …
Authors
Chui DHK; Luo H-Y; Clarke BJ
Journal
Hemoglobin, Vol. 12, No. 5-6, pp. 459–463
Publisher
Taylor & Francis
Publication Date
January 1988
DOI
10.3109/03630268808991635
ISSN
0363-0269