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Reversal of direct oral anticoagulants: Guidance...
Journal article

Reversal of direct oral anticoagulants: Guidance from the Anticoagulation Forum

Abstract

Two specific reversal agents for direct oral anticoagulants (DOACs) have been approved in the United States: idarucizumab for dabigatran reversal and andexanet alfa for apixaban and rivaroxaban reversal. Non-specific prohemostatic agents such as prothrombin complex concentrate (PCC) and activated PCC have also been used for DOAC reversal. The goal of this document is to provide comprehensive guidance from the Anticoagulation Forum, a North …

Authors

Cuker A; Burnett A; Triller D; Crowther M; Ansell J; Van Cott EM; Wirth D; Kaatz S

Journal

American Journal of Hematology, Vol. 94, No. 6, pp. 697–709

Publisher

Wiley

Publication Date

6 2019

DOI

10.1002/ajh.25475

ISSN

0361-8609