Prospective evaluation of a policy of early discontinuation of antibiotics and discharge from hospital in children with cancer who develop fever

Objective. To prospectively evaluate a set of clinical care schemata that would facilitate early discontinuation of antibiotics and hospital discharge in children with cancer admitted for management of infection. Methods. Based on recent published studies identifying children with fever and neutropenia who are at ‘‘low risk’’ for infection, and studies where antibiotics were discontinued quickly in such populations. We developed a set of four …