Journal article
Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins
Abstract
BACKGROUND & AIMS: Wheat-related disorders, a spectrum of conditions induced by the ingestion of gluten-containing cereals, have been increasing in prevalence. Patients with celiac disease have gluten-specific immune responses, but the contribution of non-gluten proteins to symptoms in patients with celiac disease or other wheat-related disorders is controversial.
METHODS: C57BL/6 (control), Myd88-/-, Ticam1-/-, and Il15-/- mice were placed on …
Authors
Caminero A; McCarville JL; Zevallos VF; Pigrau M; Yu XB; Jury J; Galipeau HJ; Clarizio AV; Casqueiro J; Murray JA
Journal
Gastroenterology, Vol. 156, No. 8, pp. 2266–2280
Publisher
Elsevier
Publication Date
6 2019
DOI
10.1053/j.gastro.2019.02.028
ISSN
0016-5085