Journal article
CK8/18 expression, the basal phenotype, and family history in identifying BRCA1‐associated breast cancer in the Ontario site of the Breast Cancer Family Registry
Abstract
BACKGROUND: BRCA1-associated breast cancer had been shown to be morphologically and genetically distinct from sporadic cancers. The aim of this study was to determine the association of CK8/18 with BRCA1-associated tumors and if, by using CK8/18 and basal biomarkers in conjunction with morphologic features and family history characteristics, the specificity of the BRCA1-associated tumor profile in a pathologically well-characterized cohort …
Authors
Mulligan AM; Pinnaduwage D; Bane AL; Bull SB; O'Malley FP; Andrulis IL
Journal
Cancer, Vol. 117, No. 7, pp. 1350–1359
Publisher
Wiley
Publication Date
April 2011
DOI
10.1002/cncr.25642
ISSN
1097-0142