Journal article
Circulating tumor DNA alterations in patients with metastatic castration‐resistant prostate cancer
Abstract
BACKGROUND: Because cell-free DNA (cfDNA) analysis facilitates the noninvasive genomic profiling of metastatic castration-resistant prostate cancer (mCRPC), the authors evaluated the association between cfDNA alterations and outcomes and evolution with therapy.
METHODS: Patients with mCRPC underwent cfDNA genomic profiling using Guardant360, which examines major cancer-associated genes. Clinical factors, therapy information, failure-free …
Authors
Sonpavde G; Agarwal N; Pond GR; Nagy RJ; Nussenzveig RH; Hahn AW; Sartor O; Gourdin TS; Nandagopal L; Ledet EM
Journal
Cancer, Vol. 125, No. 9, pp. 1459–1469
Publisher
Wiley
Publication Date
5 2019
DOI
10.1002/cncr.31959
ISSN
1097-0142