Journal article
Type I interferon restricts type 2 immunopathology through the regulation of group 2 innate lymphoid cells
Abstract
Dysregulation of group 2 innate lymphoid cells has been linked to virus-induced asthma. Fritz and colleagues demonstrate that deficiency in signaling via type I interferons in these cells can lead to dysregulated type 2 immunity during respiratory viral infection.
Authors
Duerr CU; McCarthy CDA; Mindt BC; Rubio M; Meli AP; Pothlichet J; Eva MM; Gauchat J-F; Qureshi ST; Mazer BD
Journal
Nature Immunology, Vol. 17, No. 1, pp. 65–75
Publisher
Springer Nature
Publication Date
1 2016
DOI
10.1038/ni.3308
ISSN
1529-2908