Journal article
Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders
Abstract
Liability to alcohol dependence (AD) is heritable, but little is known about its complex polygenic architecture or its genetic relationship with other disorders. To discover loci associated with AD and characterize the relationship between AD and other psychiatric and behavioral outcomes, we carried out the largest genome-wide association study to date of DSM-IV-diagnosed AD. Genome-wide data on 14,904 individuals with AD and 37,944 controls …
Authors
Walters RK; Polimanti R; Johnson EC; McClintick JN; Adams MJ; Adkins AE; Aliev F; Bacanu S-A; Batzler A; Bertelsen S
Journal
Nature Neuroscience, Vol. 21, No. 12, pp. 1656–1669
Publisher
Springer Nature
Publication Date
12 2018
DOI
10.1038/s41593-018-0275-1
ISSN
1097-6256