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Effect of the concentration of Ca2+ in the...
Journal article

Effect of the concentration of Ca2+ in the suspending medium on the responses of human and rabbit platelets to aggregating agents

Abstract

The effect of the concentration of Ca2+ in the suspending medium of human and rabbit platelets on aggregation, release of 14C-serotonin, and TXB2 formation in response to ADP, thrombin, 1-O-alkyl-2-acetyl-sn-glyceryl-3-phosphorylcholine (PAF), collagen and arachidonic acid was studied in either platelet-rich plasma anticoagulated with D-phenylalanyl-prolyl-arginyl chloromethylketone (PPACK) or citrate, or suspensions of washed platelets in …

Authors

Packham MA; Bryant NL; Guccione MA; Kinlough-Rathbone RL; Mustard JF

Journal

Thrombosis and Haemostasis, Vol. 62, , pp. 968–976

Publication Date

November 1989

ISSN

0340-6245