Journal article
Decreased Platelet Membrane Fluidity Due to Glycation or Acetylation of Membrane Proteins
Abstract
Platelets from diabetic subjects and animals are hypersensitive to agonists in vitro. Membrane fluidity modulates cell function and previously we observed reduced membrane fluidity in platelets from diabetic patients associated with hypersensitivity to thrombin. We previously reported that decreased fluidity of isolated platelet membranes from diabetic patients is associated with increased glycation of platelet membrane proteins, but not with …
Authors
Winocour PD; Watala C; Perry DW; Kinlough-Rathbone RL
Journal
Thrombosis and Haemostasis, Vol. 68, No. 05, pp. 577–582
Publisher
Thieme
Publication Date
1992
DOI
10.1055/s-0038-1646320
ISSN
0340-6245