Journal article
Impact of Standard Bacterial Vaginosis Treatment on the Genital Microbiota, Immune Milieu, and Ex Vivo Human Immunodeficiency Virus Susceptibility
Abstract
BACKGROUND: Genital immunology is a key determinant of human immunodeficiency virus (HIV) susceptibility. Both factors are modulated by bacterial vaginosis (BV) and, to some extent, by Lactobacillus iners, the genital Lactobacillus spp. that predominates in African, Caribbean, and other Black (ACB) women. We conducted a clinical trial to assess the impact of oral metronidazole treatment on the genital immune parameters of HIV acquisition risks …
Authors
Joag V; Obila O; Gajer P; Scott MC; Dizzell S; Humphrys M; Shahabi K; Huibner S; Shannon B; Tharao W
Journal
Clinical Infectious Diseases, Vol. 68, No. 10, pp. 1675–1683
Publisher
Oxford University Press (OUP)
Publication Date
May 2, 2019
DOI
10.1093/cid/ciy762
ISSN
1058-4838