Journal article
Brain adenylate cyclase activity in the amphetamine sensitized rat
Abstract
Behaviour was augmented in rats by treatment with 10 mg/kgm d-amphetamine twice a day for 10 days. A greater activation of adenylate cyclase was found in dopamine rich areas of these rats brains than in normal controls when the enzyme was tested with sodium fluoride and quanylimidodiphosphate. These results parallel similar findings in the brains of schizophrenics obtained at post mortem and support the use of amphetamine sensitization in rats …
Authors
Mamelak M; Chiu S; Mishra R
Journal
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Vol. 9, No. 5-6, pp. 721–724
Publisher
Elsevier
Publication Date
1 1985
DOI
10.1016/0278-5846(85)90048-x
ISSN
0278-5846