Development of deoxycorticosterone-salt induced hypertension in rats without unilateral nephrectomy

Three weeks of deoxycorticosterone (DOC)-salt treatment in rats without surgical operation such as unilateral nephrectomy caused changes of systolic blood pressure development which can be grouped in three categories: (a) the hypertensive group with blood pressure levels consistently higher than 160 mmHg; (b) the normotensive group with blood pressure levels consistently lower than 140 mmHg; and (c) the labile hypertensive group with blood …