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A new view of K+-induced contraction in rat aorta:...
Journal article

A new view of K+-induced contraction in rat aorta: the role of Ca2+ binding

Abstract

Strong, K+-induced contractions of rat aorta in Ca-free, Mg-free media were not accompanied by increased intracellular calcium concentration, [Ca2+]i, whereas such contractions in the presence of the divalent cations were correlated with rising [Ca2+]i as assessed by fura-2. At the same time, calcium channel blockers, a modulator of Ca2+-binding proteins, and a modulator of actin polymerization, inhibited all types of K+-induced contractions. …

Authors

Kravtsov GM; Bruce IC; Wong TM; Kwan C-Y

Journal

Pflügers Archiv - European Journal of Physiology, Vol. 446, No. 5, pp. 529–540

Publisher

Springer Nature

Publication Date

8 2003

DOI

10.1007/s00424-003-1096-x

ISSN

0031-6768