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Forskolin, cyclic nucleotides and positive...
Journal article

Forskolin, cyclic nucleotides and positive inotropism in isolated papillary muscles of the rabbit

Abstract

The effects of forskolin, isoprenaline, sodium nitroprusside and the frequency of stimulation were examined on cyclic nucleotide levels and tension responses in rabbit isolated right ventricular papillary muscles. Increasing the frequency of stimulation from 0.01 Hz to 1.6 Hz induced positive inotropic responses that were not obviously related to alterations in the level of either cyclic AMP or cyclic GMP. Isoprenaline induced rapid, …

Authors

Rodger IW; Shahid M

Journal

British Journal of Pharmacology, Vol. 81, No. 1, pp. 151–159

Publisher

Wiley

Publication Date

1 1984

DOI

10.1111/j.1476-5381.1984.tb10755.x

ISSN

0007-1188