Journal article
Prostaglandin H Synthase 2 Expression in Airway Cells from Patients with Asthma and Chronic Obstructive Pulmonary Disease
Abstract
Products of the prostaglandin H synthase (PGHS) metabolic pathway are thought to play a role in the pathogenesis of asthma. We determined the level of expression of the constitutive (PGHS-1) and inducible (PGHS-2) isoforms of the enzyme in induced sputum and bronchial biopsies of patients with asthma, patients with chronic obstructive pulmonary disease (COPD), and unaffected control subjects by immunocyto- and immunohistochemistry. …
Authors
TAHA R; OLIVENSTEIN R; UTSUMI T; ERNST P; BARNES PJ; RODGER IW; GIAID A
Journal
American Journal of Respiratory and Critical Care Medicine, Vol. 161, No. 2, pp. 636–640
Publisher
American Thoracic Society
Publication Date
February 1, 2000
DOI
10.1164/ajrccm.161.2.9811063
ISSN
1073-449X