Journal article
Hyperplastic effects of aerosolized sodium metabisulfite on rat airway mucus-secretory epithelial cells
Abstract
The ability of aerosolized sodium metabisulfite to induce hypertrophic and hyperplastic changes in rat airway secretory epithelial cells was investigated. A 10% solution of sodium metabisulfite was aerosolized into a Plexiglas exposure chamber, using an ultrasonic humidifier. The level of SO2 gas generated by this apparatus was measured to be 500 ppm. Measured levels of neutral and acidic mucous glycoproteins in extracts from tracheal and lung …
Authors
Pon DJ; van Staden CJ; Boulet L; Rodger IW
Journal
Canadian Journal of Physiology and Pharmacology, Vol. 72, No. 9, pp. 1025–1030
Publisher
Canadian Science Publishing
Publication Date
September 1, 1994
DOI
10.1139/y94-143
ISSN
0008-4212