Journal article
Fluorescent Nanorods and Nanospheres for Real‐Time In Vivo Probing of Nanoparticle Shape‐Dependent Tumor Penetration
Abstract
Shape dependent: Fluorescent quantum‐dot‐based nanospheres and nanorods with identical hydrodynamic size and surface properties but different aspect ratios were developed for real‐time in vivo tumor imaging. The nanorods exhibited superior transport and distribution into mammary tumors in vivo versus nanospheres of similar plasma half‐life.
Authors
Chauhan VP; Popović Z; Chen O; Cui J; Fukumura D; Bawendi MG; Jain RK
Journal
Angewandte Chemie International Edition, Vol. 50, No. 48, pp. 11417–11420
Publisher
Wiley
Publication Date
November 25, 2011
DOI
10.1002/anie.201104449
ISSN
1433-7851